Pharmaceutically active compounds represent a large class of water pollutants. The
most commonly detected pharmaceutically active compound in aqueous recipients
is diclofenac. There are several methods for removing these compounds, and one of
the most commonly used is sorption. Different materials are used as sorbents. The
sorption of pharmaceutically active compounds into polysaccharides is determined
by the type of polysaccharide and the method of its modification, as well as the
structure of the drug itself. In this work, samples of selectively oxidized cellulose
with 0.057 mmol/g COOH and 0.0845 mmol/g CHO (sample-OC1) and 0.063
mmol/g COOH and 0.0875 mmol/g CHO (sample-OC2) were used as
polysaccharide sorbent. They were obtained by oxidation of the cellulose using
TEMPO reagent for 2 hours at a temperature of 25±1°C. Sorption of diclofenac
was performed from an aqueous solution of concentrations c=1,5∙10-3 and 3,0∙10-3
mol/L at a temperature of 25±1°C for 48 hours. The amounts of bound drug were
determined spectrophotometrically at a wavelength of λmax = 276 nm. The
maximum amount of bound drug after 24h was 0.0465 mmol/g OC (from solution
c=3,0∙10-3 mol/L, on a sample OC2). The paper studies the possibility of using a
TEMPO oxidized cellulose for sorption of diclofenac. Also, the paper studies
influence of the content of COOH and CHO groups and the sorption properties of
OC, the concentration of diclofenac solution and the duration of sorption on its
sorption.
