Pyridone aryl azo dyes belong to a class of compounds that have wide application, not only as agents
for coloring various materials in many branches of the industry but also in medicine as biologically
active compounds. It has been proven that they have anti-tumor, anti-inflammatory, and antituberculosis activity and are widely used for therapeutic purposes. Their application can highly
depend on the inter- or intra- molecular interactions that occur between the dissolved compound and
the surrounding medium. Therefore, the study of these interactions is of great importance for newly
synthesized compounds. The spectrophotometric method can be used to examine intermolecular
interactions thoroughly by studying the solvatochromic properties of newly synthesized compounds
in different molecular environments. To this end, absorption spectra of seven newly synthesized aryl
azo pyridone dyes based on 5-((disubstituted phenyl)diazenyl)-6-hydroxy-4-methyl-2-oxo-1,2-
dihydropyridine-3-carbonitrile were recorded in ten solvents of different properties. The spectra were
recorded in the range from 300 to 600 nm and showed one absorption maximum. By applying
different models based on the principle of multiple linear correlations of solvatochromic energies
(LSER method), information about the effects of certain interactions that take place between the
tested compounds and the surrounding medium were obtained.
