This study aimed to evaluate the pulpal response after pulp
capping using experimental nanostructured calcium aluminate
cement (ALBO-CA) and tricalcium silicate cement Biodentine
(Septodont, Saint Maur des Fosses, France). Class I cavities
were prepared on 72 teeth (36 first upper molars and 36-second
upper molars) in 18 Wistar strain rats. The dental pulp was
capped in 36 teeth with experimental ALBO-CA (group A) and
36 teeth with Biodentine (group B). All cavities were restored
with glass ionomer. After 28 days animals were sacrificed and
the following were analyzed: the inflammatory response of the
pulp, the presence of bacteria, and the formation of a dentinal
bridge. After 28 days, bacteria were not present. Mann-Whitney
U test did not show a statistically significant difference in the
inflammatory response of the pulp between the groups (U
= 640.00; Z = 0.105; p = 0.916). The chi-square test did not
show a statistically significant difference in the formation of
the dentinal bridge between the examined groups (Chi-square =
1,443; p = 0,230). ALBO-CA and Biodentine had similar effects
on inflammation, pulp response, and formation of dental bridges
in rats.